We have previously shown that a higher number of mature eosinophils express ST2 in a direct IL-33-induced asthma model compared to control mice [22] and we recently observed a higher number of ST2+ eosinophils and IL-33-responsive ILC2s in the bone marrow in an IL-33- dependent acute protease allergen model [33]. The gene discussed is IL33; the disease is asthma.