BRAF and melanoma: HSP90 is required for folding of a number of oncoproteins relevant to melanoma, including BRAFV600E but not a wild-type variant of BRAF, and components of the phosphatidylinositol 3-kinase (PI3K)/AKT, wingless-type (WNT)/β-catenin, unfolded protein response (UPR), and nuclear factor-kappa B (NF-κB) signaling pathways [16,17,18].