For the following experiments, we have chosen three representative genes, C-X-C motif chemokine ligand 8 (CXCL8), cyclin D1 (CCND1), and BCL-2-like 1 (BCL2L1), as they (i) encode proteins involved in different cellular processes, i.e., invasion/migration and angiogenesis, proliferation and survival, respectively, and (ii) are characterized as relevant to melanoma. This evidence concerns the gene CXCL8 and melanoma.