HK2 and gastrointestinal stromal tumor: We observed that inhibition of glycolysis by adding 100 μM of 3-BP, an inhibitor of hexokinase 2 (HK2), increased loosely adherent/floating cells in GIST 882R and GIST 48, while the GIST 882, T1, and T1R cells were not affected at the same concentration (Figure 4a).