Microarray analysis of HCC cell lines demonstrated that other genes are additionally influenced in SP, compared with non-SP cells, such as GATA6 which is associated with embryonic development and hepatocytic differentiation and some ABC transporter genes, including ABCG2, ABCB1, and CEACAM6, linked to chemoresistance to doxorubicin, 5-fluorouracil, and gemcitabine, in addition to epithelial and mesenchymal markers. This evidence concerns the gene ABCG2 and hepatocellular carcinoma.