In patients with hepatocellular carcinoma (HCC) recurrence, the majority of hepatic stem/progenitor cell (HSC/HPC) biomarkers are overexpressed, including cytokeratin 19, ABCG2, CD133, Nestin, and CD44, and angiogenesis agents CD34, VEGF, and PD-ECGF. The gene discussed is CD44; the disease is hepatocellular carcinoma.