The study of Lazarova et al. focusing on colorectal cancer cells showed that vimentin is differentially expressed, depending on the metastatic state of the tumor, and proposed the hypothesis that the expression of vimentin in colonic neoplastic cells may correlate with the stage of neoplastic progression and that vimentin is the critical factor in colonic neoplastic progression [54]. The gene discussed is VIM; the disease is colorectal cancer.