GSTP1 and colorectal cancer: On the contrary, Figure 6d shows an obvious and significant sensitization of both colorectal cancer cell lines to cisplatin after GSTP1 knockdown (EC50: HCT-8, 7.10 μM; HCT-8ox: 12.79 μM) compared to either the negative control (EC50: HCT-8, 19.10 μM; HCT-8ox, 34.28 μM) or cells without knockdown (EC50: HCT-8, 21.04 μM; HCT-8ox, 38.19 μM).