An overexpression of eicosanoid-producing enzymes, like cyclooxygenases (COX-1 and COX-2) and lipoxygenases (5-LOX, 12-LOX and 15-LOX) in gliomas and meningiomas, suggesting the promotion of tumorigenesis, has been reported before [19]. The gene discussed is ALOX15; the disease is glioma.