Upon target cell recognition, NK cells may mediate target cell lysis via direct release of lytic granules or engagement of death receptor-related apoptosis through tumor necrosis factor (TNF), Fas ligand (FasL), and TNF-related apoptosis-inducing ligand (TRAIL) production, whose surface receptors are commonly expressed by tumor cells [9]. The gene discussed is FASLG; the disease is neoplasm.