Compared with downregulated PTGIS expression, elevated PTGIS expression was associated with worse OS or disease free survival (DFS) in ACC (adrenocortical carcinoma), BLCA (bladder urothelial carcinoma), COAD (colon adenocarcinoma), GBM (glioblastoma multiforme), KIRP (kidney renal papillary cell carcinoma), LUSC (lung squamous cell carcinoma), OV (ovarian serous cystadenocarcinoma) and STAD (stomach adenocarcinoma). The gene discussed is PTGIS; the disease is squamous cell lung carcinoma.