PTGIS and breast cancer: Interestingly, compared with low PTGIS expression, high expression of PTGIS indicated a better survival prognosis for overall survival (OS) (hazard ratio [HR]=0.63, 95% confidence interval [CI]=0.44 to 0.90, P=0.012) and disease specific survival (DSS) (HR=0.60, 95% CI=0.40 to 0.90, P=0.013) in breast cancer (Figure 2A and 2B).