As for upregulated miRNA, miR‐125a regulates FOXP3 expression and modulates the different inflammatory signaling pathways; this might be associated with thymoma with myasthenia gravis.20 High expression of miR‐34a might modulate thymoma cell differentiation and development.21 As for downregulated miRNA, miR‐106 can target MEK2, which might affect the thymus' immune function.22 Meanwhile, MEK2 is a member of the MAPK signaling pathway, which was also upregulated in type A and AB thymoma, as previously mentioned. Here, MAP2K2 is linked to myasthenia gravis.