Due to the indicated importance of alveolar macrophages during hRSV and hMPV infections and the modulation of CD1d expression found in the lungs from hRSV- and hMPV-infected mice, further studies in NKT activation with alveolar macrophages are required and may provide more details about the mechanisms associated with the modulation of the disease by these viruses by NKT cells. This evidence concerns the gene CD1D and infection.