Co‐transfer of Gata3‐negative Tregs from OX40cre Gata3fl/fl, or Foxp3EGFP‐cre Gata‐3fl/fl mice, with naive T cells into Rag1−/− recipients induces severe colitis and weight loss,60, 81 suggesting that Tregs use Gata3 to limit tissue inflammation. The gene discussed is GATA3; the disease is colitis.