According to previous researches, FOXK1 promotes liver cancer,19 breast cancer,28 esophageal cancer,29 colorectal cancer,30 prostate cancer31 etc. Whether TMPO‐AS1 could modulate HCC progression by targeting FOXK1/miR‐329‐3p axis was worth investigating. The gene discussed is TMPO; the disease is hepatocellular carcinoma.