When downregulating TMPO‐AS1, the expression of E‐cadherin was increased, and that of N‐cadherin, MMP2 as well as MMP7 was decreased, indicating that EMT process of HCC cells was obstructed by knocking downTMPO‐AS1 (Figure S1B). The gene discussed is MMP2; the disease is hepatocellular carcinoma.