BRAF and melanoma: This condition is associated with neurofibrin (NF1), NRAS, BRAF, non-V600E, or KIT-associated mutations, which shows high rates of mutation, while non-CSD melanoma usually affects areas of the body that are more frequently exposed to intermittent sunlight (e.g., the torso), and it is observed in younger individuals (<55 years old) who do not show significant solar elastic tissue disease.