SPRED1 and melanoma: Figure 2(b) shows a fragment that was notably absent in the melanoma genome. Table S3 contains records of genes that were notably deleted on each fragment, for example, CDKN2A was significantly missing in segment 9p21.3 (q value = 1.1011E − 198), PTEN was significantly missing in segment 10q23.31 (q value = 1.02E − 14), and SPRED1 was significantly missing in segment 15q14 (q value = 1.23E − 09).