Furthermore, identification of YAP1–KMT2A fusion-positive soft tissue sarcomas with sclerosing epithelioid sarcoma-like histologic and ultrastructural features raises the question of whether these sarcomas should be classified as a distinct entity related to or within the spectrum of sclerosing epithelioid fibrosarcoma. The gene discussed is KMT2A; the disease is epithelioid sarcoma.