By immunohistochemistry, tumor cells demonstrated strong nuclear cyclin D1 expression (Fig. 1g) and multifocal smooth muscle actin staining but were negative for MUC4, ERG, CD34, S-100 protein, desmin, STAT6, CD45, MDM2, CDK4, ALK, and ROS1. The gene discussed is PTPRC; the disease is neoplasm.