GATA3 and breast carcinoma: To clarify the mechanisms underlying the functional role of lncRNA LOC645166 in adriamycin resistance, we screened for potential interaction transcription factors that met the following requirements: Firstly, it is associated with tumourigenesis and chemotherapy resistance in breast cancer; Secondly, it can potentially regulate transcription of GATA3 and finally, it can be bound to lncRNA.