XCL1 is often cosecreted with IFN-γ, CCL3, CCL4 and CCL5 by CD8+ T and NK cells and has emerged as a critical component of the Th1 immune response against several infections.64 Dorner et al16 showed that XCL1 is a selective chemoattractant for murine splenic DCs highly efficient in cross presentation. The gene discussed is CCL3; the disease is infection.