We found a positive correlation between urinary ALCAM with both global disease activity (vs SLEDAI, r = 0.487, p < 0.001) and renal disease activity (vs rSLEDAI, r = 0.552 p < 0.001; vs SLICC RAS, r = 0.584, p < 0.001) (Fig. 2a–c). This evidence concerns the gene ALCAM and kidney disorder.