SYNE1 and metastatic prostate carcinoma: Of the 61,999 men with non-metastatic prostate cancer included in the study, 10,963 were grouped in CPG1 (17.7%) as the lowest risk group, 13,588 in CPG2 (21.9%), 9452 in CPG3 (15.2%), 12,831 in CPG4 (20.7%), and 15,165 in CPG5 (24.5%) as the highest risk group (Fig. 1).