ZNF16 and neoplasm: Cytoplasmic expression of FAM83H was significantly associated with distant metastasis (p = 0.022), tumor stage (p = 0.040), histologic grade (p = 0.003), and the expression of nuclear ZNF16 (p = 0.019) and cytoplasmic ZNF16 (p = 0.009) (Table 1).