These include, erytrocyte membrane protein brain 4.1 (EPB41), which encodes proteins of the red cell membrane skeleton and is associated with hematologic disorders in humans related with variable degrees of anaemia [68], and ferroportin (SLC40A1), a gene that is relevant for iron homeostasis [69] and was previously reported to be under selection in African taurine cattle [14]. This evidence concerns the gene EPB41 and anemia (phenotype).