Tumor cell migration could be stimulated by MMP3 secretion in NPC tumor cells [42], In our study, miR-30e-5p inhibited the expressions of vimentin, Snail, MMP2 and MMP3, and promoted cell migration and invasion inhibition, while the function of miR-30e-5p could be reversed by MTA1, indicating that the function of miR-30e-5p on cell migration and invasion of NPC cells might be related to migration-related factors (vimentin and Snail) and invasion-related factors (MMP2 and MMP3). Here, MMP3 is linked to nasopharyngeal carcinoma.