There are several suggestions regarding the effect of EBV/HPV co-infection on the outcome of the cervical lesion, Al-Thawadi et al., (2018) reported the co-expression of LMP1 and E6 genes of EBV and high-risk HPVs to be an important factor associated with squamous cell carcinomas and overexpression of diffused Id-1, which is an important regulator of cell invasion and metastasis. The gene discussed is PDLIM7; the disease is coinfection.