P-gp plays an important role to pump various chemotherapeutic agents out of MDR carcinoma cells, including the following drugs: taxanes, Vinca alkaloids, anthracyclines, and epipodophyllotoxins (Sarkadi et al., 2006; Alameh et al., 2019; Qiu et al., 2019; Liu et al., 2010; Lopez-Chavez et al., 2009). This evidence concerns the gene PGP and carcinoma.