MMP2 and neoplasm: Since the MMP-2 cross-interface molecular transport leads to peritumoural micro-fibres degradation at the micro-scale, we explored this degradation explicitly at the cell scale, remarking here at the same time that this complements the previous modelling framework introduced and discussed in Shuttleworth and Trucu (2019) where the fibres degradation was only considered on the bulk of the tumour at the macro-scale.