Zhou et al. (2017) found that tunicamycin induced endoplasmic reticulum stress (ERS) and consequently autophagy and apoptosis in human esophageal cancer cells, which rendered them more sensitive to cisplatin. Xu et al. (2018) demonstrated that Rab5a enhanced cisplatin resistance through inhibition of autophagy in GC cells. This evidence concerns the gene RAB5A and esophageal cancer.