The glioma were induced by co-activation of oncogenic Ras and the PI3K pathway by the expression of UAS-PtenRNAi; UAS-RasV12 under the glia specific Repo-Gal4 driver (henceforth referred to as repoGal4>UAS-PtenRNAi; UAS-RasV12; UAS-GFP). Here, LGALS4 is linked to central nervous system cancer.