In order to test the interactions between Tep and Yki in the context of glioma growth, we wanted to examine if overexpression of Yki could rescue the effects of loss of Tep1 in our glioma model using repoGAL4. However, Yki overexpression in glia (repoGal4>UAS-GFP/UAS-Yki) caused lethality in early second instar larval stage, limiting our ability to perform a genetic epistasis experiment. This evidence concerns the gene TEP1 and central nervous system cancer.