Prognostic analysis revealed that high expression of HIST1H2BK would lead to a short overall survival in patients with LGG (Figure 2C, P < 0.05), and the expression level of HIST1H2BK was not associated with the prognosis of patients with GBM (Figure 2D, P > 0.05). This evidence concerns the gene H2BC12 and glioblastoma.