Mutations occurred less frequently (<1.5%) in the other 11 genes (CTNNB1, AKT1, ERBB2, ERBB4, FGFR1, ALK, MAP2K1, NOTCH1, DDR2, FGFR3, and FGFR2), consistent with the “tail effect” associated with NGS profiling of tumor samples (15) (Figure 1A). The gene discussed is ERBB2; the disease is neoplasm.