Although previous studies have shown that these RNAs have important roles in multiple biological processes, especially for MFAP5 and miR-200b-3p in tumorigenesis, more studies are needed that are focused on the mechanistic interactions between MFAP5, miR-200b-3p and AC005154.6, especially regarding their functional relationships in the occurrence and progression of CRC. Here, MFAP5 is linked to colorectal carcinoma.