NKs also release cytokines and chemokines including IFN-γ, TNF-α, GM-CSF, MIP1-α, RANTES, IL-6, and CCL5 thus attracting and activating monocytes, macrophage, T cells, DCs, and neutrophils to promote an anti-tumor response (13, 75). The gene discussed is CSF2; the disease is neoplasm.