Ten years later, a BsAb (anti-CD19 × anti-CD3) was studied in a clinical trial for the treatment of non-Hodgkin’s lymphoma (NHL) (2) and it took until 2009 for the approval of catumaxomab (anti-epCAM × anti-CD3) for the treatment of patients with malignant ascites (3). The gene discussed is CD19; the disease is non-Hodgkin lymphoma.