CRP and IgA glomerulonephritis: As examples of DAMP-mediated complement activation, we could mention the CP induction by C-reactive protein (CRP) or Pentraxin-3 (12) (8); in IgA nephropathy, LP can be triggered by IgA (13), and after ischemia/reperfusion injury (IRI), L-fucose induced LP on stressed cells (7).