ALOX5 and infection: In the presence of Zileuton, the differences in LXA4 and LTB4 expression between H37Rv and H37RvΔ1768 infection were alleviated after infection for 12 h (Figures 10H,I), suggesting that Rv1768 stimulates 5-LO expression, thus, affecting LXA4 and LTB4 expression levels.