In contrast, 5-LO expression showed no significant changes between H37Rv- and H37RvΔ1768-infection in S100A9–/– RAW264.7 cells (Figure 10A, right), suggesting that Rv1768 stimulates macrophage 5-LO expression after infection for 12 h, and that this stimulation depends on S100A9. Here, S100A9 is linked to infection.