In a post-status epilepticus animal model of mesial temporal lobe epilepsy, the expression of core-clock genes is found to be dysregulated during epileptogenesis: the expression of PER1 and CRY1 increases in the early post-status epilepticus condition compared to the control condition and decreases to the baseline level in epileptic condition; the expression of BMAL1, CLOCK, and CRY2 gradually decreases during epileptogenesis (17). Here, CLOCK is linked to status epilepticus.