TG and type 2 diabetes mellitus: Compared with the T2DM group, 183 circRNAs were upregulated and 64 circRNAs were downregulated in T2DM patients with DEP. Hsa-circRNA-003251 and hsa-circRNA-015115 might play important roles in the circRNA-miRNA-mRNA network associated with DEP by acting as hsa-miR-761 sponges. In addition to the above two RNAs, hsa-circRNA-100918 and hsa-circRNA-001520 might be involved in the Wnt signaling pathway of thyroid hormone.