reported that treatment with I-BET-762, another BET inhibitor, markedly alleviated taurolithocholic acid-induced pancreatitis and POA plus ethanol AP, but not caerulein hyperstimulation pancreatitis (Huang et al., 2017), suggesting that different BET inhibitor may exert their anti-inflammatory effects through different mechanisms. The gene discussed is DNER; the disease is pancreatitis.