Hence, the odds ratio (OR) for HLA-B*15:02 association with CBZ SJS–TEN was 181 (95% confidence interval: 8.7–3785, p = 6.9 × 10-8), validating a significant association for HLA-B*15:02 in Singapore Chinese and Malays, as has been observed in a number of other Southeast Asian countries. Here, HLA-B is linked to toxic epidermal necrolysis.