CHI3L1 and vascular dementia: Furthermore, according to the National Institute of Neurological and Communicative Disorders and Stroke and the Alzheimer’s Disease and Related Disorders Association (NINCDS-ADRDA) (Olsson et al., 2013), YKL-40 and sCD14 were increased in MCI patients who converted to vascular dementia (VaD) (p = 0.029 and p = 0.008), but not to AD.