In another study using murine CAR T cells specific for B7H6 (a tumour-specific activating ligand for the NKp30 receptor [87]), the TH1 phenotype-associated transcription factor T-bet was found to increase the efficacy of their CAR T cells in controlling NKp30+ RMA tumours in mice [88]. The gene discussed is NCR3LG1; the disease is neoplasm.