Higher numbers and frequencies of IL-17-expressing Th17 T-cells have been reported in the blood of CLL patients compared with HC which is in line with elevated plasma levels of IL-17 in CLL, although numbers of Th17 T-cells were much lower than Th1 and Th2 cells [20, 21]. The gene discussed is IL17A; the disease is B-cell chronic lymphocytic leukemia.