RHOA and endometrial cancer: In a recent study, Frank et al.17 showed that p190A induced contact inhibition of cell proliferation in Madin-Darby Canine Kidney cells by repressing the transcription of YAP target genes through the RhoA-LATS-YAP cascade, suggesting that the impact of p190A on the Hippo-YAP pathway is not limited to endometrial cancer-derived cells.