This phenomenon provides a plausible explanation for the better survival in these cancer patients.19,20 Considering that the immune-related interleukin-6/signal transducer and activator of transcription 3 and IFNα/β pathways were markedly elevated in p190A-KO endometrial cancer cells, the cytotoxic T-lymphocyte infiltration status should be investigated in p190A-mutated endometrial cancer. The gene discussed is STAT3; the disease is cancer.