PDX1 and familial pancreatic carcinoma: Among the 25 pancreatic cancer GWAS SNPs, 7 (rs2816938 (~ 11 kb upstream of NR5A2), rs10094872 (~ 28 kb upstream of MYC), rs9581943 (200 bp upstream of PDX1), and 4 chromosome 13q22.1 SNPs: rs4885093, rs9573163, rs9543325, rs9573166) showed statistically significant association with pancreatic cancer risk (Table 3 and the results for the entire 25 SNPs can be found in Supplementary Table 2).