The results showed that the expression of CXCR4 on AML Tregs was significantly higher than that of the controls (44.15% [range: 19.78 to 71.78%] vs 5.20% [range: 3.10 to 25.75%], P = 0.0190), while the expression of CXCR7 showed no significant differences between the two groups (3.40% [range: 2.10 to 4.10%] vs 2.50% [range; 1.88 to 4.85%], P = 0.8861) (Fig. 3g-h). The gene discussed is ACKR3; the disease is acute myeloid leukemia.