Inthe KEGG analysis, related genes were involved in the HH signaling pathway,basal cell carcinoma pathway, hippo signaling pathway, and TGF-β signalingpathway (Figure 2C).TCTN3 is a protein required for tumorigenesis in association with HH signalingpathway; and thus, we hypothesized that C militaris–inducedapoptosisin NSCLC cells via inactivation of the HH signaling pathway is causedby inhibition of TCTN3. This evidence concerns the gene TGFB1 and non-small cell lung carcinoma.