CXCR2 and neoplasm: Leukocyte recruitment to the tumor site is mediated by inflammatory chemokines from the CXC subfamily (CXCL1, -2, -5, -6, and -8) as well as from the CC group (CCL2, -3, and -5), which attract leukocytes: neutrophils bearing receptors CXCR2 and CCR2-positive monocytes.