In humans, the TGFB3 gene is involved in arrhythmogenic right ventricular dysplasia (ARVD) familial 1 (ARVD1) (OMIM#107970) [6,7], now being referred to as arrhythmogenic right ventricular cardiomyopathy (ARVC). This evidence concerns the gene TGFB3 and Arrhythmogenic right ventricular dysplasia.