This was the case of a 57-year-old patient with TPM3-related nemaline myopathy with his first respiratory symptoms at the age of 40, who had had muscle weakness since early childhood [152], or similarly in a 56-year-old female with TPM2-related CFTD, evaluated for dyspnea and muscle weakness, who had delayed motor milestones, a hoarse voice and an easy fatigability since her early life [153]. This evidence concerns the gene TPM2 and nemaline myopathy.