TREM1 and hepatocellular carcinoma: TREM-1 expression was confirmed in vivo in macrophages, DCs, and LCs infiltrating hypoxic inflammatory tissues [31,110,201] and in TAMs infiltrating HIF-1+ glioblastoma and hepatocellular carcinoma (HCC) [202,205] (see Section 6 for details), suggesting the potential relevance of this molecule as a regulator of MP functions under hypoxic conditions.