PDXP and metabolic dysfunction-associated steatotic liver disease: The protective role of vitamin B6 against hepatic lipid accumulation is sustained by the evidence that vitamin B6 administration reduced the accumulation of lipids in livers of high-fat diet-fed Apoe−/− mice [90] and also that patients affected by nonalcoholic fatty liver disease (NAFLD), a metabolic condition strictly linked to insulin resistance [94], exhibited decreased PLP levels [95].