PANK1 and Neurodegeneration: Pantothenate Kinase-associated Neurodegeneration (PKAN, OMIM #234200) belongs to the heterogeneous group of neurodegenerative diseases known as Neurodegeneration with Brain Iron Accumulation (NBIA) [1,2], characterized by a massive iron accumulation in the basal ganglia, progressive dystonia and parkinsonism, cognitive decline and psychiatric disturbances.